Spring 2002 -- Vol. 19, No. 1

FACES OF PENN STATE

Robert Simpson
Verne M. Willaman Chair in Molecular Biology

Molecular biologist Robert Simpson studies the structure of chromatin and its impact on gene regulation. His meticulous nature and work ethic have boosted his research, making him an international leader in the field.

For more than 20 years, Robert Simpson’s role as an international leader in research on the structure of chromatin and its impact on gene regulation has been unquestioned. When it comes to chromatin, a protein-DNA compound found in the nucleus of cells, Simpson knows the answers—or how to find them.

Not surprisingly, Robert Schlegel, professor and head of the Department of Biochemistry and Molecular Biology at Penn State refers to Simpson as a “walking encyclopedia.” Still, Simpson sets himself apart because he knows he can always learn more. Next semester, he plans to use the first sabbatical of his career to visit the University of Massachusetts and conduct studies with biologist Christopher Woodcock.

“He’s opened my eyes to the power of electron microscopy,” Simpson says. “We’ve looked at four genes in active and inactive states, and that was the first time they have been observed under an electron microscope. I’m hoping to make the most of my time, and hoping that an old dog can learn new techniques.”

An efficient research effort aimed at increasing his knowledge seemingly typifies Simpson’s personality and his approach to science. He’s meticulous and talented, a professor who understands the importance of preparation and the value of an almost-never-ending work ethic.

Since his arrival at Penn State, adding more talent to a vibrant group of researchers focusing on gene regulation, his in-vivo studies of yeast have provided a perfect complement to other in-vitro experiments in the Department of Biochemistry and Molecular Biology and throughout the Eberly College of Science.

Additionally, Simpson enjoys his role as an elder statesman and mentor in the college, and he has not slacked off in his research in order to shoulder those duties. His interest in research remains as intense as it was 30 years ago, when he left a medical practice and a career as an M.D. for a career as a researcher.

“Medical practice was always enjoyable, but research was more absorbing,” Simpson says. “Also, with the way the medical practices have changed, it was probably a good move.”

Likewise, Simpson’s move to Penn State has been positive and productive for him, for fellow faculty members, and for graduate and undergraduate students at Penn State.

While Simpson remains hands-on with his research, he occasionally finds time away from work for carpentry, designing Bible boxes for family members, and fishing. He even builds Shaker-style furniture pieces when he has time.

His experience as a sailor in the Navy gets put to use almost daily, too. He has not been on the water in a while, but believes the mentality of sailing transfers to his work.

“You’re always looking for more speed from your boat; any time there is another boat about your size going your way, it's a race,” Simpson says. “We’re always competing in science as well.”

-- Steve Sampsell

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